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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50303045'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303045((R)-3-(1-(5-fluoropyrimidin-2-yl)ethylamino)-6-met...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JAK2 using 2 mM ATP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303045((R)-3-(1-(5-fluoropyrimidin-2-yl)ethylamino)-6-met...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of JAK2 using 5 mM ATP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed