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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50303054'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303054((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50: <3nMAssay Description:Inhibition of JAK2 using 2 mM ATP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303054((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303054((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JAK2 using 2 mM ATP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed