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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50602437'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Zhuhai United Laboratories

Curated by ChEMBL
LigandPNGBDBM50602437(CHEMBL5172397)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant human JAK2 using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC as substrate incubated for 40 mins in presence of Mg/ATP mixture b...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Zhuhai United Laboratories

Curated by ChEMBL
LigandPNGBDBM50602437(CHEMBL5172397)
Affinity DataIC50:  4.65E+3nMAssay Description:Inhibition of JAK2 signalling in human whole blood assessed as inhibition of GM-CSF stimulated STAT5 phosphorylation in CD33+ monocytes preincubated ...More data for this Ligand-Target Pair
In DepthDetails PubMed