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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM153195'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM153195
(US8993756, 5-6)
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Affinity Data
IC50: 0.220nM
T: 2°C
Assay Description:
The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
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