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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM466343'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM466343((8S)-N-[(2S)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...)
Affinity DataEC50:  8.30nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM466343((8S)-N-[(2S)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...)
Affinity DataEC50:  3.30nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent