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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50433252'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50433252(CHEMBL2376144)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of JAK3 (unknown origin) using [33gammaP]ATP and Biotin-KAIETDKEYYTVKD as substrate incubated for 10 mins prior to substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50433252(CHEMBL2376144)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to JAK3 (unknown origin) by ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed