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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3 [512-1124]' and Ligand = 'BDBM420028'
TargetTyrosine-protein kinase JAK3 [512-1124](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM420028(US10487083, Example B)
Affinity DataIC50:  13.4nMAssay Description:11-point dosing series were made for each compound by serially diluting 1:3 or 1:4 in DMSO, with point 12 being a DMSO control. From the serial dilut...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent