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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Tec' and Ligand = 'BDBM291522'
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))TBA
LigandPNGBDBM291522(1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of FLAG-tagged TEC autophosphorylation in HEK293 cells incubated for 2 hrs by MSD electrochemiluminescence immunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))TBA
LigandPNGBDBM291522(1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)...)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human cytoplasmic full length His-tagged TEC expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))TBA
LigandPNGBDBM291522(1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)...)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to DNA-tagged recombinant TEC (unknown origin) measured after 1 hr by biotinylated-ligand affinity bead-based qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed