Found 8 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ZAP-70' and Ligand = 'BDBM2579' TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal GST-fused human recombinant full length ZAP70 (1 to 619 residues) expressed in baculovirus-infected Sf21 cells using FAM-22 ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ZAP70 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of ZAP70 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 12.4nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataKd: 44nMAssay Description:Binding constant for ZAP70 kinase domainMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
University Of Chinese Academy Of Science
Curated by ChEMBL
University Of Chinese Academy Of Science
Curated by ChEMBL
Affinity DataKd: 44nMAssay Description:Binding constant for ZAP70 kinase domainMore data for this Ligand-Target Pair
