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Found 10 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM13990'
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.90E+3nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.92E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate measured every 30 secs for 15 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phosphate as substrate monitered eve...More data for this Ligand-Target Pair
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair