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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM479314'
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM479314((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50:  13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM479314((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50:  13nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics

US Patent
LigandPNGBDBM479314((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...)
Affinity DataIC50:  13nMAssay Description:The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent