Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM53072'
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM53072((5Z)-3-allyl-5-(3-ethyl-1,3-benzothiazol-2-ylidene...)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of GST-tagged SHP2 PTP domain (unknown origin) using phospho-EGFR Asp-Ala-Asp-Glu-Tyr[PO3H2]-Leu-Ile-Pro-Gln-Gln-Gly as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM53072((5Z)-3-allyl-5-(3-ethyl-1,3-benzothiazol-2-ylidene...)
Affinity DataIC50:  4.52E+4nMAssay Description:Inhibition of wild type GST-tagged full-length SHP2 (unknown origin) using phospho-EGFR Asp-Ala-Asp-Glu-Tyr[PO3H2]-Leu-Ile-Pro-Gln-Gln-Gly as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed