Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM595843' TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
