Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM608820'
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM608820(US11702411, Compound 3 | US11702411, Example 3)
Affinity DataIC50:  275nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM608820(US11702411, Compound 3 | US11702411, Example 3)
Affinity DataIC50:  461nMAssay Description:The inhibition of SHP2 by compounds of the present disclosure (concentrations varying from 0.00005-10 μM) was monitored using an assay in which ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent