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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 2 [E242G,S244A,Q278R,I281T,K282R,R316G,P318T,Y321CH323L]' and Ligand = 'BDBM50438882'
LigandPNGBDBM50438882(10-Phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dion...)
Affinity DataIC50:  7.10E+4nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed