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Found 2 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 28' and Ligand = 'BDBM482105'
TargetUbiquitin carboxyl-terminal hydrolase 28(Homo sapiens)
Valo Early Discovery

US Patent
LigandPNGBDBM482105(US10913753, Compound I-172 | US20230365583, Compou...)
Affinity DataIC50: <200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 28(Homo sapiens)
Valo Early Discovery

US Patent
LigandPNGBDBM482105(US10913753, Compound I-172 | US20230365583, Compou...)
Affinity DataIC50: <1.00E+3nMAssay Description:USP28 (at 1 nM) was pre-incubated with different concentrations of inhibitors or DMSO as a control in 50 mM Tris pH 8, 50 mM NaCl, 0.002% Tween-20, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent