Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50228245'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228245(CHEMBL34945 | LY-186126)
Affinity DataKi:  40nMAssay Description:Displacement [3H]LY-186,126 from phosphodiesterase 4 of myocardial vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228245(CHEMBL34945 | LY-186126)
Affinity DataIC50:  120nMAssay Description:Inhibition of sarcoplasmic reticulum Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228245(CHEMBL34945 | LY-186126)
Affinity DataKd:  4.10nMAssay Description:Binding affinity for Phosphodiesterase 4 of canine myocardial vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228245(CHEMBL34945 | LY-186126)
Affinity DataKd:  3.90nMAssay Description:Binding affinity for sarcoplasmic reticulum phosphodiesterase 4 of canine ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed