Report error Found 2 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50495736'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair