Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50040348'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50040348(8-Amino-1,3-bis-cyclopropylmethyl-3,7-dihydro-puri...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50040348(8-Amino-1,3-bis-cyclopropylmethyl-3,7-dihydro-puri...)
Affinity DataEC50:  910nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed