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Found 3 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50240404'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human PDE4B expressed in insect sf9 cells using [3H]-cAMP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human PDE4B catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed