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Found 1 Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112]' and Ligand = 'BDBM15300'
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15300(dihydropyridazinone 6c | ethyl N-{4-[(4R)-4-methyl...)
Affinity DataIC50:  8.5nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed