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Found 4 Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50335843'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50335843((5R,11aR)5-(2,4-Dichlorophenyl)-2-ethyl-5,6,11,11a...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant PDE5A-mediated hydrolysis of cGMP after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50335843((5R,11aR)5-(2,4-Dichlorophenyl)-2-ethyl-5,6,11,11a...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant PDE5 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50335843((5R,11aR)5-(2,4-Dichlorophenyl)-2-ethyl-5,6,11,11a...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant PDE5 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50335843((5R,11aR)5-(2,4-Dichlorophenyl)-2-ethyl-5,6,11,11a...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant PDE5A-mediated hydrolysis of cGMP after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed