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Found 3 Enz. Inhib. hit(s) with Target = 'rRNA adenine N-6-methyltransferase' and Ligand = 'BDBM50291836'
TargetrRNA adenine N-6-methyltransferase(Staphylococcus aureus (strain N315))
International Institute Of Molecular And Cell Biology

Curated by ChEMBL
LigandPNGBDBM50291836(CHEMBL4177311)
Affinity DataKi:  1.11E+5nMAssay Description:Competitive inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli BL21(DE3) in presence of [methyl-3H]SAMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetrRNA adenine N-6-methyltransferase(Staphylococcus aureus (strain N315))
International Institute Of Molecular And Cell Biology

Curated by ChEMBL
LigandPNGBDBM50291836(CHEMBL4177311)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetrRNA adenine N-6-methyltransferase(Staphylococcus aureus (strain N315))
International Institute Of Molecular And Cell Biology

Curated by ChEMBL
LigandPNGBDBM50291836(CHEMBL4177311)
Affinity DataKd:  40nMAssay Description:Inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli BL21(DE3) assessed as decrease of protein binding to [gamma-33P]AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed