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TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM429505(Remdesivir | US20240034730, Compound Remdesivir | ...)
Affinity DataEC50:  1.10E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484213(Inhibitor 21 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.08E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448349(Perampanel, 5)
Affinity DataEC50:  2.50E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448349(Perampanel, 5)
Affinity DataEC50:  1.50E+3nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448361(Perampanel, 14)
Affinity DataEC50:  3.20E+3nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448369(Perampanel, 21)
Affinity DataEC50:  1.13E+4nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448371(Perampanel, 23)
Affinity DataEC50:  840nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448374(Perampanel, 26)
Affinity DataEC50:  2.00E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448374(Perampanel, 26)
Affinity DataEC50:  980nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448375(Perampanel, 27)
Affinity DataEC50:  1.10E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM429505(Remdesivir | US20240034730, Compound Remdesivir | ...)
Affinity DataEC50:  590nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM429505(Remdesivir | US20240034730, Compound Remdesivir | ...)
Affinity DataEC50:  770nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476977(Inhibitor 2 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.51E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476977(Inhibitor 2 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.50E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476978(Inhibitor 3 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.76E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476978(Inhibitor 3 of SARS-CoV-2 Mpro)
Affinity DataEC50:  980nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476981(Inhibitor 4 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.20E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476981(Inhibitor 4 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.10E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476988(Inhibitor 9 of SARS-CoV-2 Mpro)
Affinity DataEC50:  730nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476988(Inhibitor 9 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.70E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476993(Inhibitor 13 of SARS-CoV-2 Mpro)
Affinity DataEC50: >4.00E+4nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataEC50:  530nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.20E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484209(Inhibitor 17 of SARS-CoV-2 Mpro)
Affinity DataEC50:  820nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro)
Affinity DataEC50:  3.20E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.00E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476999(Inhibitor 19 of SARS-CoV-2 Mpro)
Affinity DataEC50:  175nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476999(Inhibitor 19 of SARS-CoV-2 Mpro)
Affinity DataEC50:  80nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM429505(Remdesivir | US20240034730, Compound Remdesivir | ...)
Affinity DataEC50:  770nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
In DepthDetails Article