Affinity DataKi: 1nM ΔG°: -50.9kJ/mole IC50: 3nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
Affinity DataKi: 180nM ΔG°: -38.1kJ/mole IC50: 330nM EC50: 9.10nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
Affinity DataKi: 320nM ΔG°: -36.7kJ/mole IC50: 620nM EC50: 8.70nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
Affinity DataKi: 510nM ΔG°: -35.6kJ/mole IC50: 980nM EC50: 19nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
Affinity DataKi: 570nM ΔG°: -35.3kJ/mole IC50: 1.30E+3nM EC50: 6.20nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
Affinity DataKi: 580nM ΔG°: -35.2kJ/mole IC50: 1.10E+3nM EC50: 13nMpH: 7.4 T: 2°CAssay Description:In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+4nM IC50: 3.20E+4nMpH: 7.4Assay Description:Human recombinant adrenergic β2 receptors expressed in CHO cells are used in modified Tris-HCl buffer pH 7.4. A 50 aliquot is incubated with 0.2...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00130nMAssay Description:Inhibition of beta2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0501nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0794nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Agonistic activity for Beta-2 adrenergic receptor was assessed by it's inhibitory effect on spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. IC50, the mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Niigata College of Pharmacy
Curated by PDSP Ki Database
Niigata College of Pharmacy
Curated by PDSP Ki Database
Affinity DataIC50: 0.100nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.158nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contracti...More data for this Ligand-Target Pair
Affinity DataIC50: <0.300nMAssay Description:Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Antagonist activity at ADRB2 endogenously expressed in HEK293 cells transfected with cAMP FRET biosensor assessed as inhibition of cimaterol-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Antagonist activity at ADRB2 endogenously expressed in HEK293 cells transfected with cAMP FRET biosensor assessed as inhibition of cimaterol-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.724nMAssay Description:Antagonist activity at beta2 adrenergic receptor (unknown origin) expressed in HEK293 cell assessed as inhibition of isoproterenol-induced cAMP produ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Displacement of [3H](-)CGP12177 from human recombinant Beta-2 adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Displacement of [3H]CGP 12177 from human recombinant beta2 adrenergic receptor expressed in CHO cells measured after 120 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.794nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of beta2 adrenoreceptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of radiolabeled iodocyanopindolol from recombinant beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at beta2 adrenergic receptor (unknown origin) expressed in HEK293 cell assessed as inhibition of isoproterenol-induced cAMP produ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair