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TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50394214(CHEMBL2159162)
Affinity DataIC50:  0.430nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424188(CHEMBL2312079)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424182(CHEMBL2312073)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424184(CHEMBL2312075)
Affinity DataIC50:  2.90nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424186(CHEMBL2312077)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424183(CHEMBL2312074)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424175(CHEMBL2312066)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50380914(S-2367 | VELNEPERIT)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424179(CHEMBL2312070)
Affinity DataIC50:  7.10nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424181(CHEMBL2312072)
Affinity DataIC50:  9.60nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424191(CHEMBL2312063)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50365416(CHEMBL1585484)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424180(CHEMBL2312071)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149143(3-(2-Benzo[b]thiophen-2-yl-ethyl)-1-aza-bicyclo[2....)
Affinity DataIC50:  23nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149143(3-(2-Benzo[b]thiophen-2-yl-ethyl)-1-aza-bicyclo[2....)
Affinity DataIC50:  23nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149143(3-(2-Benzo[b]thiophen-2-yl-ethyl)-1-aza-bicyclo[2....)
Affinity DataIC50:  23nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424174(CHEMBL2312065)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149146((S)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo...)
Affinity DataIC50:  26nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424177(CHEMBL2312068)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424189(CHEMBL2312080)
Affinity DataIC50:  49nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149145(3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo[2.2...)
Affinity DataIC50:  59nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424173(CHEMBL2312064)
Affinity DataIC50:  80nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424185(CHEMBL2312076)
Affinity DataIC50:  96nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424178(CHEMBL2312069)
Affinity DataIC50:  98nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201282(3-(cyclohexylmethyl)-N,N-dimethyl-3,4-dihydro-2H-b...)
Affinity DataIC50: >100nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201300(3-(4-cyclohexylbutyl)-N,N-dimethyl-3,4-dihydro-2H-...)
Affinity DataIC50: >100nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201298(2-phenyl-N-((3-(pyrrolidin-1-yl)-3,4-dihydro-2H-be...)
Affinity DataIC50: >100nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201297(2-phenyl-N-((3-(piperidin-1-yl)-3,4-dihydro-2H-ben...)
Affinity DataIC50: >100nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201290(CHEMBL435158 | N,N-dimethyl-3-((methyl(phenethyl)a...)
Affinity DataIC50: >100nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201288(3-((4-methoxyphenethylamino)methyl)-N,N-dimethyl-3...)
Affinity DataIC50: >100nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149148(3-Benzo[b]thiophen-2-ylmethyl-1-aza-bicyclo[2.2.2]...)
Affinity DataIC50:  110nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424187(CHEMBL2312078)
Affinity DataIC50:  112nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149147(2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-1-benzo[b]thiophe...)
Affinity DataIC50:  130nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149147(2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-1-benzo[b]thiophe...)
Affinity DataIC50:  130nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149147(2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-1-benzo[b]thiophe...)
Affinity DataIC50:  130nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149140(3-(Naphthalen-2-ylmethoxy)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50:  150nMAssay Description:Binding affinities of the compound for the alpha 7 nicotinic acetylcholine receptor was determined in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149151(3-(3-Benzo[b]thiophen-2-yl-propyl)-1-aza-bicyclo[2...)
Affinity DataIC50:  370nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149138((R)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo...)
Affinity DataIC50:  515nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Mus musculus (Mouse))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50424190(CHEMBL2312081)
Affinity DataIC50:  608nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149149(3-(Naphthalen-1-ylmethoxy)-1-aza-bicyclo[2.2.2]oct...)
Affinity DataIC50:  730nMAssay Description:Binding affinities of the compound for the alpha 7 nicotinic acetylcholine receptor was determined in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149150(3-(2,4-Dimethoxy-benzyl)-[2,3']bipyridinyl | CHEMB...)
Affinity DataIC50:  760nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149142((1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[b]thiophen-2-...)
Affinity DataIC50:  950nMAssay Description:Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Welfide

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration of the compound against binding of 5-hydroxytryptamine 1A receptor from striata of male Wistar rats by displacement of [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50086859(CHEMBL147226 | N-((R)-1-Phenethyl-pyrrolidin-2-ylm...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50086862(6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against binding of 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50086860(3-Methylsulfanyl-N-((R)-1-phenethyl-pyrrolidin-2-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against binding of 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50086853(CHEMBL82652 | Cyclohexanecarboxylic acid ((R)-1-ph...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Welfide

Curated by ChEMBL
LigandPNGBDBM50086859(CHEMBL147226 | N-((R)-1-Phenethyl-pyrrolidin-2-ylm...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration of the compound against binding of 5-hydroxytryptamine 1A receptor from striata of male Wistar rats by displacement of [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Welfide

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration of the compound against binding of 5-hydroxytryptamine 1A receptor from striata of male Wistar rats by displacement of [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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