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TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152512(CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...)
Affinity DataIC50:  0.810nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152515(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataIC50:  1.20nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095207(CHEMBL430154 | [6-(4-Benzhydryl-pyrazol-1-ylmethyl...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284372(CHEMBL11211 | {5-[2-(N',N'-Diphenyl-hydrazinocarbo...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataIC50:  10nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284377(CHEMBL11746 | {5-[2-(4-Benzhydryl-pyrazol-1-yl)-et...)
Affinity DataIC50:  18nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284370(CHEMBL10836 | [6-(N',N'-Diphenyl-hydrazinocarbonyl...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  27nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152509(CHEMBL363984 | {1-[4-(2,3-Dihydro-benzofuran-2-ylm...)
Affinity DataIC50:  30nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152514(CHEMBL365829 | {1-[4-(Chroman-2-ylmethoxy)-benzoyl...)
Affinity DataIC50:  30nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152508(CHEMBL364593 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataIC50:  30nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284378(CHEMBL11765 | [6-(4-Benzhydryl-pyrazol-1-ylmethyl)...)
Affinity DataIC50:  40nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152516(CHEMBL184684 | {1-[4-(Benzo[1,3]dioxol-2-ylmethoxy...)
Affinity DataIC50:  50nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Affinity DataIC50:  50nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataIC50:  120nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284366((6-{2-[(E)-Benzhydryloxyimino]-butyl}-5,6,7,8-tetr...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095205((6-{2-[(E)-Benzhydryloxyimino]-pentyl}-5,6,7,8-tet...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284371(CHEMBL11291 | [5-(2-Benzhydrylideneaminooxy-ethyl)...)
Affinity DataIC50:  210nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284367(((S)-6-{2-[(E)-Benzhydryloxyimino]-propyl}-5,6,7,8...)
Affinity DataIC50:  220nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152506(CHEMBL186735 | {2-Methyl-1-[4-(2-phenoxy-ethoxy)-b...)
Affinity DataIC50:  250nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataIC50:  270nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152507(CHEMBL182555 | [1-(4-Butoxy-benzoyl)-2-methyl-1H-i...)
Affinity DataIC50:  300nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284363(((R)-6-{2-[(E)-Benzhydryloxyimino]-propyl}-5,6,7,8...)
Affinity DataIC50:  380nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284374(CHEMBL266622 | [5-(3-Benzhydryloxy-propyl)-5,6,7,8...)
Affinity DataIC50:  460nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284355(CHEMBL10470 | [5-(3-Benzhydryloxyimino-propyl)-5,6...)
Affinity DataIC50:  600nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284355(CHEMBL10470 | [5-(3-Benzhydryloxyimino-propyl)-5,6...)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284360(CHEMBL10742 | [6-(2-Benzhydryloxyimino-ethyl)-5,6,...)
Affinity DataIC50:  650nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284360(CHEMBL10742 | [6-(2-Benzhydryloxyimino-ethyl)-5,6,...)
Affinity DataIC50:  650nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150972(4-[1-(4-Butoxy-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  910nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152511(CHEMBL365243 | [1-(4-Benzyloxy-benzoyl)-2-methyl-1...)
Affinity DataIC50:  1.30E+3nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101853((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150974(3-[1-(4-Butoxy-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150973(CHEMBL362541 | [1-(4-Butoxy-benzoyl)-5-methoxy-2-m...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284376(CHEMBL11480 | {5-[2-(4-Benzhydryl-pyrazol-1-yl)-et...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284365((5-{3-[(E)-Benzhydryloxyimino]-hexyl}-5,6,7,8-tetr...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284363(((R)-6-{2-[(E)-Benzhydryloxyimino]-propyl}-5,6,7,8...)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284368((6-Benzhydrylideneaminooxymethyl-5,6,7,8-tetrahydr...)
Affinity DataIC50:  2.40E+3nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150968(CHEMBL364421 | [1-(3-Butoxy-benzoyl)-5-methoxy-2-m...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150975(CHEMBL183933 | [1-(4-Butoxy-benzoyl)-2,5-dimethyl-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284353(CHEMBL10442 | [6-((Z)-5,5-Diphenyl-pent-2-enyl)-5,...)
Affinity DataIC50:  3.00E+3nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50047491(CHEMBL11811 | Sodium; (E)-2-methyl-3-(4-pyridin-3-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against Thromboxane A2 synthase in human platelet microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284358(CHEMBL10856 | [6-((E)-5,5-Diphenyl-pent-2-enyl)-5,...)
Affinity DataIC50:  3.10E+3nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150966(CHEMBL182572 | [1-(4-Butoxy-benzoyl)-2-methyl-1H-i...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150966(CHEMBL182572 | [1-(4-Butoxy-benzoyl)-2-methyl-1H-i...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284357(CHEMBL10261 | [3-(4-Benzhydryloxyimino-butyl)-phen...)
Affinity DataIC50:  3.90E+3nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150967(1-(4-Butoxy-benzoyl)-5-methoxy-2-methyl-1H-indole-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284369(CHEMBL11571 | [5-(4-Benzhydryloxy-butyl)-5,6,7,8-t...)
Affinity DataIC50:  4.20E+3nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50150976(5-[1-(4-Butoxy-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of mouse Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284361(CHEMBL10564 | [6-((E)-4-Hydroxy-5-phenyl-pent-2-en...)
Affinity DataIC50:  4.90E+3nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
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