Compile Data Set for Download or QSAR
maximum 50k data
Found 1276 of ic50 data for polymerid = 10938
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547894(CHEMBL4760292 | US11377438, Example 172)
Affinity DataIC50:  0.300nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547894(CHEMBL4760292 | US11377438, Example 172)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547925(CHEMBL4798938)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547896(CHEMBL4777598 | US11377438, Example 184)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547896(CHEMBL4777598 | US11377438, Example 184)
Affinity DataIC50:  0.5nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560005(US11377438, Example 53)
Affinity DataIC50:  0.800nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547926(CHEMBL4753280)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529546(2,4-dichloro-6-(4-chloro-2- | US11203571, Compound...)
Affinity DataIC50:  0.800nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547885(CHEMBL4781110 | US11377438, Example 18)
Affinity DataIC50:  0.900nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547885(CHEMBL4781110 | US11377438, Example 18)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529543(2,4-dichloro-6-(4-fluoro-2-methoxyphenoxy)-N-(3-su...)
Affinity DataIC50:  0.900nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161329(US10087143, Compound 114 | US10738009, Compound 11...)
Affinity DataIC50:  1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529537(2-(4-fluoro-2-methoxyphenoxy)-N-(3-sulfamoylphenyl...)
Affinity DataIC50:  1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161329(US10087143, Compound 114 | US10738009, Compound 11...)
Affinity DataIC50:  1nMAssay Description:1) Pre-spotted compounds (in neat DMSO) into compound plates. Vehicle control (neat DMSO), the positive control (20 mM DMSO stock tetracaine, 125 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161329(US10087143, Compound 114 | US10738009, Compound 11...)
Affinity DataIC50:  1nMAssay Description:Sodium channels are voltage-dependent proteins that can be activated by inducing membrane voltage changes by applying electric fields. The electrical...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547890(CHEMBL4745699 | US11377438, Example 46)
Affinity DataIC50:  1nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50330935(CHEMBL1277958 | N-(m-Tolyl)-6-(4-ethoxyphenyl)-pyr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161329(US10087143, Compound 114 | US10738009, Compound 11...)
Affinity DataIC50:  1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529544(2,4-dichloro-6-(4-fluoro-2- | US11203571, Compound...)
Affinity DataIC50:  1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547890(CHEMBL4745699 | US11377438, Example 46)
Affinity DataIC50:  1nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM181203(US9139529, 46 | US9783501, Compound 46)
Affinity DataIC50:  1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529525(4,5-dichloro-2-(4-fluoro-2-methoxyphenoxy)-N-(3-su...)
Affinity DataIC50:  1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560161(US11377438, Example 201)
Affinity DataIC50:  1.30nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547929(CHEMBL4744908)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560001(US11377438, Example 49)
Affinity DataIC50:  1.40nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547924(CHEMBL4750365)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560008(US11377438, Example 55)
Affinity DataIC50:  1.40nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547928(CHEMBL4787299)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560073(US11377438, Example 115)
Affinity DataIC50:  1.60nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547886(CHEMBL4764433 | US11377438, Example 19)
Affinity DataIC50:  1.60nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547886(CHEMBL4764433 | US11377438, Example 19)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547927(CHEMBL4756380)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547930(CHEMBL4782190)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560162(US11377438, Example 202)
Affinity DataIC50:  1.90nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560089(US11377438, Example 131)
Affinity DataIC50:  2nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50330948(CHEMBL1277959 | N-(2-Methylbenzyl)-6-(4-ethoxyphen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50330949(CHEMBL1277877 | N-(3,5-Dimethylphenyl)-6-(4-ethoxy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50329223(CHEMBL1270797 | N-(3,5-dimethylphenyl)-5-(4-(trifl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161373(US10087143, Compound 158 | US10738009, Compound 15...)
Affinity DataIC50:  2nMAssay Description:1) Pre-spotted compounds (in neat DMSO) into compound plates. Vehicle control (neat DMSO), the positive control (20 mM DMSO stock tetracaine, 125 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM181223(US9139529, 66 | US9783501, Compound 66)
Affinity DataIC50:  2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161373(US10087143, Compound 158 | US10738009, Compound 15...)
Affinity DataIC50:  2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50507856(CHEMBL4483603)
Affinity DataIC50:  2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529461(2-(4-fluoro-2-methoxyphenoxy)-N-(3-sulfamoylphenyl...)
Affinity DataIC50:  2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547922(CHEMBL4761578)
Affinity DataIC50:  2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161373(US10087143, Compound 158 | US10738009, Compound 15...)
Affinity DataIC50:  2nMAssay Description:Sodium channels are voltage-dependent proteins that can be activated by inducing membrane voltage changes by applying electric fields. The electrical...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM529541(2-(4-fluoro-2-methylphenoxy)- | US11203571, Compou...)
Affinity DataIC50:  2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547921(CHEMBL4785523)
Affinity DataIC50:  2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560124(US11377438, Example 164 | US11377438, Example 165)
Affinity DataIC50:  2.10nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560006(US11377438, Example 54)
Affinity DataIC50:  2.10nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for Nav1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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