Affinity DataIC50: 0.0370nMAssay Description:Inhibition of human integrin alpha-4-beta-1-mediated MOLT4 cell adhesion to biotin-conjugated CS-1 peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of human integrin alpha-4-beta-1-mediated MOLT4 cell adhesion to biotin-conjugated CS-1 peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.305nMAssay Description:Inhibition of human integrin alpha-4-beta-1-mediated MOLT4 cell adhesion to biotin-conjugated CS-1 peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)p...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration of the compound against VLA-4 receptor using human VCAM-VLA-4 binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair