TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 6.60nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 8.20nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Binding affinity to human alpha1beta2gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 17nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 28nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 31nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 34nMAssay Description:Activity at human GABAA alpha-1-beta-2-gamma-2L expressed in Xenopus oocytes assessed as potentiation of GABA currentsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 36nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 41nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 56nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 69nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Positive allosteric modulation of human GABAA receptor alpha1beta2gamma2L expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induce...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 81nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 85nMAssay Description:Binding affinity to human alpha1beta2gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 92nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 93nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 95nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Allosteric modulation of GABAA alpha1beta2gamma2 (unknown origin) expressed in Xenopus oocytes assessed as potentiation of GABA-induced current respo...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 107nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 118nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 125nMAssay Description:Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 127nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 133nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 135nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 136nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 191nMAssay Description:Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 198nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Positive allosteric modulation of human GABAA receptor alpha1beta2gamma2L expressed in Xenopus laevis oocytes assessed as potentiation of GABA chlori...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Positive allosteric modulation of recombinant human GABA receptor alpha1beta2gamma2 expressed in CHO cells at 30 uM in presence of GABA and measured ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 208nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 225nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 237nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 238nMAssay Description:Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Positive allosteric modulation of recombinant human GABA receptor alpha1beta2gamma2 expressed in CHO cells at 30 uM in presence of GABA and measured ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 258nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Bern
Curated by ChEMBL
University Of Bern
Curated by ChEMBL
Affinity DataEC50: 266nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 290nMAssay Description:Modulation of human GABA-A alpha1beta2gamma2 expressed in xenopus oocytes assessed as potentiation of GABA-evoked chloride currentsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys
Curated by ChEMBL
Cocensys
Curated by ChEMBL
Affinity DataEC50: 291nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair