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Report error Found 167 of ec50 for UniProtKB: P13569
LigandChemical structure of BindingDB Monomer ID 297409BDBM297409(US10117858, Example 16 | US20240058315, Example 17)
Affinity DataEC50:  8nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297409BDBM297409(US10117858, Example 16 | US20240058315, Example 17)
Affinity DataEC50:  10nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297396BDBM297396(US10117858, Example 2 | 3-Amino-6-bromo-5-trifluor...)
Affinity DataEC50:  15nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526510BDBM526510(US11186566, Compound 49)
Affinity DataEC50:  20nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526467BDBM526467(US11186566, Compound 4)
Affinity DataEC50:  20nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526476BDBM526476(US11186566, Compound 15)
Affinity DataEC50:  20nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526477BDBM526477(US11186566, Compound 16)
Affinity DataEC50:  20nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526464BDBM526464(US11186566, Compound 17 | US11186566, Compound 1)
Affinity DataEC50:  30nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526511BDBM526511(US11186566, Compound 50)
Affinity DataEC50:  30nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526484BDBM526484(US11186566, Compound 23)
Affinity DataEC50:  30nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526489BDBM526489(US11186566, Compound 28)
Affinity DataEC50:  30nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526492BDBM526492(US11186566, Compound 31)
Affinity DataEC50:  30nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297403BDBM297403(US10117858, Example 12 | 3-Amino-6-methoxy-5-trifl...)
Affinity DataEC50:  35nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297401BDBM297401(US10117858, Example 11 | 3-Amino-6-(4-fluoro-pheny...)
Affinity DataEC50:  37nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526514BDBM526514(US11186566, Compound 53)
Affinity DataEC50:  40nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526471BDBM526471(US11186566, Compound 10)
Affinity DataEC50:  40nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526493BDBM526493(US11186566, Compound 32)
Affinity DataEC50:  40nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297406BDBM297406(US10117858, Example 7 | 3-Amino-6-(4-fluoro-phenyl...)
Affinity DataEC50:  40nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526475BDBM526475(US11186566, Compound 14)
Affinity DataEC50:  40nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526512BDBM526512(US11186566, Compound 51)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526516BDBM526516(US11186566, Compound 55)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526468BDBM526468(US11186566, Compound 5)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526519BDBM526519(US11186566, Compound 58)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526523BDBM526523(US11186566, Compound 64 | US11186566, Compound 63)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526504BDBM526504(US11186566, Compound 43)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526503BDBM526503(US11186566, Compound 42)
Affinity DataEC50:  50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297402BDBM297402(US10117858, Example 5 | US20240058315, Example 5)
Affinity DataEC50:  50nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297407BDBM297407(US10117858, Example 15 | 5-Amino-6′-methyl-3...)
Affinity DataEC50:  51nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297398BDBM297398(US10117858, Example 3 | 3-Amino-6-bromo-5-trifluor...)
Affinity DataEC50:  55nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297408BDBM297408(US10117858, Example 8 | 3-Amino-6-(4-fluoro-phenyl...)
Affinity DataEC50:  60nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526526BDBM526526(US11186566, Compound A)
Affinity DataEC50:  60nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526502BDBM526502(US11186566, Compound 41)
Affinity DataEC50:  70nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526485BDBM526485(US11186566, Compound 24)
Affinity DataEC50:  70nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526498BDBM526498(US11186566, Compound 37)
Affinity DataEC50:  70nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526500BDBM526500(US11186566, Compound 39)
Affinity DataEC50:  70nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297400BDBM297400(US10117858, Example 6 | US10117858, Example 4 | US...)
Affinity DataEC50:  76nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526494BDBM526494(US11186566, Compound 33)
Affinity DataEC50:  80nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526501BDBM526501(US11186566, Compound 40)
Affinity DataEC50:  80nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526518BDBM526518(US11186566, Compound 57)
Affinity DataEC50:  80nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526491BDBM526491(US11186566, Compound 36 | US11186566, Compound 30)
Affinity DataEC50:  90nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 297397BDBM297397(US10117858, Example 9 | US10117858, Example 10 | U...)
Affinity DataEC50:  90nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526464BDBM526464(US11186566, Compound 17 | US11186566, Compound 1)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526466BDBM526466((S)—N-((4-Hydroxy-3-methoxyphenyl)sulfonyl)-6...)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526467BDBM526467(US11186566, Compound 4)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526468BDBM526468(US11186566, Compound 5)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526469BDBM526469(US11186566, Compound 8)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526471BDBM526471(US11186566, Compound 10)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526473BDBM526473(US11186566, Compound 12)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526475BDBM526475(US11186566, Compound 14)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 526476BDBM526476(US11186566, Compound 15)
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2022
Entry Details
US Patent

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