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TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599186(CHEMBL5201089)
Affinity DataKd:  0.0640nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599167(CHEMBL5195228)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624436(CHEMBL5429305)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by Surface Plasmon Resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91725(Carbacylamidophosphate, 2a)
Affinity DataIC50: 6.50E+5nM Kd:  2.10E+6nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91723(Carbacylamidophosphate, 1a)
Affinity DataIC50: 9.20E+5nM Kd:  4.30E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91729(Carbacylamidophosphate, 4a)
Affinity DataIC50: 1.20E+6nM Kd:  8.90E+6nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91726(Carbacylamidophosphate, 2b)
Affinity DataIC50: 5.24E+6nM Kd:  4.37E+6nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91727(Carbacylamidophosphate, 3a)
Affinity DataIC50: 4.80E+6nM Kd:  1.80E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91724(Carbacylamidophosphate, 1b)
Affinity DataIC50: 9.98E+6nM Kd:  5.06E+6nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241982(CHEMBL4093201)
Affinity DataKd:  7.30E+6nMAssay Description:Binding affinity to human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91730(Carbacylamidophosphate, 4b)
Affinity DataIC50: 1.67E+7nM Kd:  3.36E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM91728(Carbacylamidophosphate, 3b)
Affinity DataIC50: 5.56E+7nM Kd:  7.68E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed