Compile Data Set for Download or QSAR
Report error Found 1856 of ic50 for UniProtKB: P11802
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528241BDBM50528241(CHEMBL334285)
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528240BDBM50528240(CHEMBL151546)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 448940BDBM448940(N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...)
Affinity DataIC50: 0.0700nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528239BDBM50528239(CHEMBL148580)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 448950BDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50: 0.0800nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556330BDBM556330(US11351170, Example 9 | N-(5-((1-ethylpiperidin-4-...)
Affinity DataIC50: 0.100nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556335BDBM556335(US11351170, Example 12 | 5-fluoro-4-(5-fluoro-1,1-...)
Affinity DataIC50: 0.110nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556334BDBM556334(US11351170, Example 11 | 3-(4-((6-(5-fluoro-4-(5-f...)
Affinity DataIC50: 0.110nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 448926BDBM448926(1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...)
Affinity DataIC50: 0.120nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 132266BDBM132266(US8841312, 8)
Affinity DataIC50: 0.130nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455050BDBM50455050(CHEMBL4208172 | US10696678, Example 18 | US1135117...)
Affinity DataIC50: 0.140nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556329BDBM556329(US11351170, Example 8 | N-(5-((1-ethylpiperidin-4-...)
Affinity DataIC50: 0.160nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 448950BDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50: 0.170nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556328BDBM556328(US11351170, Example 7 | (S)—N-(5-(3-(dimethyl...)
Affinity DataIC50: 0.180nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 525562BDBM525562(US11174252, Compound 1)
Affinity DataIC50: 0.200nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556327BDBM556327(US11351170, Example 6 | (S)-(3-(dimethylamino)pyrr...)
Affinity DataIC50: 0.200nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528238BDBM50528238(CHEMBL4453997)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556336BDBM556336(US11351170, Example 13 | 5-fluoro-4-(5-fluoro-1,1-...)
Affinity DataIC50: 0.25nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556337BDBM556337(US11351170, Example 14 | 2-(4-(6-(5-fluoro-4-(5-fl...)
Affinity DataIC50: 0.25nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 0.260nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 0.260nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556331BDBM556331(US11351170, Example 10 | 5-fluoro-4-(5-fluoro-1,1-...)
Affinity DataIC50: 0.260nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293153BDBM50293153(TCMDC-138697 | N-(3-nitrophenyl)-4-(pyrazolo[1,5-b...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 132275BDBM132275(US8841312, 17)
Affinity DataIC50: 0.320nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 132261BDBM132261(US8841312, 3)
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 525786BDBM525786(US11174252, Compound 474)
Affinity DataIC50: 0.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 525763BDBM525763(US11174252, Compound 450)
Affinity DataIC50: 0.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 525771BDBM525771(US11174252, Compound 458)
Affinity DataIC50: 0.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455061BDBM50455061(CHEMBL4211828 | US10696678, Example 65)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 448932BDBM448932(5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444593BDBM444593(US10662186, Compound 129)
Affinity DataIC50: 0.700nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 494032BDBM494032(US10988476, Compound I-129)
Affinity DataIC50: 0.700nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 525710BDBM525710(US11174252, Compound 4)
Affinity DataIC50: 0.700nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 556326BDBM556326(US11351170, Example 2 | 1-(4-((6-(5-fluoro-4-(5-fl...)
Affinity DataIC50: 0.730nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 435712BDBM435712(US10570141, Example 1)
Affinity DataIC50: 0.800nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455057BDBM50455057(CHEMBL4215702 | US10696678, Example 20)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 132293BDBM132293(US8841312, 36)
Affinity DataIC50: 0.830nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444563BDBM444563(US10662186, Compound 82 | US10988476, Compound I-8...)
Affinity DataIC50: 0.860nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444563BDBM444563(US10662186, Compound 82 | US10988476, Compound I-8...)
Affinity DataIC50: 0.860nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 132263BDBM132263(US8841312, 5)
Affinity DataIC50: 0.910nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444569BDBM444569(US10662186, Compound 88 | US10988476, Compound I-8...)
Affinity DataIC50: 0.910nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444569BDBM444569(US10662186, Compound 88 | US10988476, Compound I-8...)
Affinity DataIC50: 0.910nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444595BDBM444595(US10662186, Compound 131 | US10988476, Compound I-...)
Affinity DataIC50: 0.910nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444595BDBM444595(US10662186, Compound 131 | US10988476, Compound I-...)
Affinity DataIC50: 0.910nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444568BDBM444568(US10662186, Compound 87 | US10988476, Compound I-8...)
Affinity DataIC50: 0.920nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444568BDBM444568(US10662186, Compound 87 | US10988476, Compound I-8...)
Affinity DataIC50: 0.920nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444566BDBM444566(US10662186, Compound 85 | US10988476, Compound I-8...)
Affinity DataIC50: 0.940nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444566BDBM444566(US10662186, Compound 85 | US10988476, Compound I-8...)
Affinity DataIC50: 0.940nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 132281BDBM132281(US8841312, 24)
Affinity DataIC50: 0.940nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 444567BDBM444567(US10662186, Compound 86 | US10988476, Compound I-8...)
Affinity DataIC50: 0.960nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

Displayed 1 to 50 (of 1856 total ) | Next | Last >>
Jump to: