TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of VEGFR2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of ALK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 6.84E+3nMAssay Description:Inhibition of MEK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MK5 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EPHB4 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERK2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TYK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RET by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MNK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cKIT by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant MEK1 expressed in insect cells after 20 minsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant MEK1 expressed in insect cells after 20 minsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in insect cells after 30 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant VEGFR1 expressed in Sf9 cells after 10 minsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in insect cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ERK2 expressed in E.coli after 15 minsMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GSK3alpha in cell free system after 60 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant VEGFR1 expressed in Sf9 cells after 10 minsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ERK1 expressed in E.coli after 30 minsMore data for this Ligand-Target Pair