Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50041599
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)
Affinity DataIC50:  0.603nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)
Affinity DataIC50:  0.708nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412319(CHEMBL457207)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412324(CHEMBL509728)
Affinity DataIC50:  3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412327(CHEMBL456142)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134099((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412321(CHEMBL456577)
Affinity DataIC50:  6nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412328(CHEMBL508321)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412325(CHEMBL458714)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134093((3aR,10R)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412330(CHEMBL456552)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50111901(2-(5-(4-methylpiperazin-1-ylsulfonyl)-2-propoxyphe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50111898(2-(2-Propoxy-phenyl)-9-propyl-1,9-dihydro-purin-6-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412329(CHEMBL515979)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412326(CHEMBL458713)
Affinity DataIC50:  18nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134094((3aR,10S)-2-Butyl-10-phenyl-3a,4,9,10-tetrahydro-2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412322(CHEMBL514402)
Affinity DataIC50:  20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134104((3aR,10S)-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-t...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412331(CHEMBL456548)
Affinity DataIC50:  20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412323(CHEMBL456370)
Affinity DataIC50:  30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134120((3aR,10R)-2-Butyl-10-thiophen-3-yl-3a,4,9,10-tetra...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  39.8nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134115((3aR,10S)-2-Butyl-10-(3-chloro-phenyl)-3a,4,9,10-t...)
Affinity DataIC50:  50nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134102((3aR,10R)-2-Butyl-10-(3-chloro-phenyl)-3a,4,9,10-t...)
Affinity DataIC50:  50nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134101((3aR,10R)-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-t...)
Affinity DataIC50:  50nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134112((3aR,10R)-2-Butyl-10-phenyl-3a,4,9,10-tetrahydro-2...)
Affinity DataIC50:  60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287548(5-Phenyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrim...)
Affinity DataIC50:  81nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134121((3aR,10R)-2-Butyl-10-pyridin-3-yl-3a,4,9,10-tetrah...)
Affinity DataIC50:  91nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134113((3aR,10R)-2-Butyl-10-furan-3-yl-3a,4,9,10-tetrahyd...)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412333(CHEMBL462983)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134110(4-((3aR,10S)-2-Butyl-1,3-dioxo-2,3,3a,4,9,10-hexah...)
Affinity DataIC50:  302nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134096((3aR,10R)-2-Butyl-10-pyridin-4-yl-3a,4,9,10-tetrah...)
Affinity DataIC50:  302nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)
Affinity DataIC50:  331nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287551(CHEMBL52245 | N-(2-(1-methyl-7-oxo-3-propyl-6,7-di...)
Affinity DataIC50:  776nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134116(4-((3aR,10R)-2-Butyl-1,3-dioxo-2,3,3a,4,9,10-hexah...)
Affinity DataIC50:  912nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)
Affinity DataIC50:  955nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412320(CHEMBL525436)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134109((3aR,10S)-2-Butyl-10-(2-methoxy-phenyl)-3a,4,9,10-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134118((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-9-methyl-3...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50287547(1-Methyl-5-(2-nitro-phenyl)-3-propyl-1,6-dihydro-p...)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50412332(CHEMBL511513)
Affinity DataIC50:  4.47E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed