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Found 29 Enz. Inhib. hit(s) with all data for entry = 50048395
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50:  0.430nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50213961(CHEMBL53739)
Affinity DataIC50:  1.20nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50:  2nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  7.70nMAssay Description:Compound was tested for its ability to displace [125I]GTI binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50213961(CHEMBL53739)
Affinity DataIC50:  8nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50:  16nMAssay Description:Compound was tested for its ability to displace [125I]GTI binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  19nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50:  20nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50:  25nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1D(Sus scrofa)TBA
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50:  49nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50:  52nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50213961(CHEMBL53739)
Affinity DataIC50:  95nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50:  320nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50:  500nMAssay Description:Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  540nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)TBA
LigandPNGBDBM50213961(CHEMBL53739)
Affinity DataIC50:  2.70E+3nMAssay Description:Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)TBA
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50:  4.10E+3nMAssay Description:Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))TBA
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50:  7.20E+3nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataIC50:  7.30E+3nMAssay Description:Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  7.90E+3nMAssay Description:Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))TBA
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))TBA
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)TBA
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))TBA
LigandPNGBDBM50213961(CHEMBL53739)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortexMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))TBA
LigandPNGBDBM50213961(CHEMBL53739)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)TBA
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)TBA
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))TBA
LigandPNGBDBM50060426(CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails