Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 710nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 370nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 2.70E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human full length C-terminus His-tagged ARH3 expressed in Escherichia coli using Bt-NAD ribosylated PARP1 substrate after 30 mins by TR...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 480nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >7.00E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 8.80E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 380nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 620nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 8.10E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 82nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 8.10E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 4.90E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 3.30E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 1.10E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 3.90E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair