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Found 32 Enz. Inhib. hit(s) with all data for entry = 50011646
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549707(CHEMBL4781856)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549704(CHEMBL4764931)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549705(CHEMBL4756311)
Affinity DataIC50:  2nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50266003(CHEMBL4091152)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549704(CHEMBL4764931)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549714(CHEMBL4762572)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549707(CHEMBL4781856)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549715(CHEMBL4760680)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549711(CHEMBL4764672)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549705(CHEMBL4756311)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549708(CHEMBL4776854)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549712(CHEMBL4790147)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549719(CHEMBL4762842)
Affinity DataIC50:  32nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549701(CHEMBL4745247)
Affinity DataIC50:  34nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549701(CHEMBL4745247)
Affinity DataIC50:  37nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549709(CHEMBL4743950)
Affinity DataIC50:  37nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50:  40nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549710(CHEMBL4745015)
Affinity DataIC50:  47nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549701(CHEMBL4745247)
Affinity DataIC50:  78nMAssay Description:Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549716(CHEMBL4749459)
Affinity DataIC50:  83nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549713(CHEMBL4790669)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549721(CHEMBL4791546)
Affinity DataIC50:  101nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549718(CHEMBL4784999)
Affinity DataIC50:  118nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549720(CHEMBL4763938)
Affinity DataIC50:  402nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549717(CHEMBL4751196)
Affinity DataIC50:  546nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549703(CHEMBL4750377)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human KMO using L-kynurenine as substrate incubated for 25 mins in presence of NADPH by microplate reader based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Mus musculus)
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549702(CHEMBL4752276)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mouse liver mitochondrial KMO using kynurenine as substrate by measuring the 3-HK formation preincubated for 5 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed