Found 107 Enz. Inhib. hit(s) with all data for entry = 50013677 TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 560nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 610nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 880nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled ass...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4(diMe) peptide as substrate measured after 60 mins by amplex red dye based HRP-coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells using tyramine as substrate by 4-AAP/3,5-DCHBS and amplex red dye based ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1B(Mus musculus)
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled a...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 3.30E+4nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by fluore...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1B(Mus musculus)
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 3.80E+4nMAssay Description:Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled a...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 4.20E+4nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1B(Mus musculus)
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 6.10E+4nMAssay Description:Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled a...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 6.40E+4nMAssay Description:Inhibition of human MAO-A expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by peroxidase-coupled ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.02E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate by 4-AAP/3,5-DCHBS and amplex red dye based ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 1.10E+5nMAssay Description:Inhibition of human MAO-A expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 2.43E+5nMAssay Description:Inhibition of N-terminal 6histidine-tagged LSD1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Peroxide prod...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by peroxidase-coupled ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by peroxidase-coupled ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by fluore...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by fluore...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of human MAO-A expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues)/His-tagged CoREST (286 to 482 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using biotinylated H3K4Me2 peptide as substrate pr...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using biotinylated H3K4Me2 peptide as substrate pr...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant LSD1 (158 to end residues) expressed in Escherichia coli using H3K4me2 peptide substrate preinc...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues) expressed in Escherichia coli BL21 (DE3) using ART(mK)QTARKSTGGKAPRKQLAGGK-...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4(diMe) peptide as substrate measured after 60 mins by amplex red dye based HRP-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human LSD1 expressed in Escherichia coli BL21 (DE3) cells using (ARTK(diMe)QTARKSTGGKAPRKQLA peptide as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Key Laboratory Of Henan Provinc
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
