Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50015749
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)
Affinity DataKi:  1.47E+4nMAssay Description:Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid as substrate assessed as inhibition constant by Michaelis-Menten equation base...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)
Affinity DataKi:  2.02E+4nMAssay Description:Noncompetitive inhibition of GOT1 (unknown origin) using alpha-Ketoglutaric acid as substrate assessed as inhibition constant by Michaelis-Menten equ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589298(CHEMBL5182428)
Affinity DataIC50:  2.92E+3nMAssay Description:Inhibition of human recombinant GOT1 using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADHMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
Affinity DataIC50:  5.39E+3nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589299(CHEMBL5170907)
Affinity DataIC50:  5.91E+3nMAssay Description:Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589293(CHEMBL5203489)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048280(6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic ac...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589296(CHEMBL5176149)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589294(CHEMBL5182989)
Affinity DataIC50:  6.54E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462552(CHEMBL4237925)
Affinity DataIC50:  8.46E+4nMAssay Description:Inhibition of human recombinant GOT1 expressed in Escherichia coli BL21 star DE3 cells using aspartic acid and alpha-ketoglutaric acid as substrates ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589297(CHEMBL5170155)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50088433(Dihydralazine)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589295(CHEMBL246237 | Phthalazin-5-Amine)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAspartate aminotransferase, cytoplasmic(Homo sapiens)
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)
Affinity DataKd:  1.65E+4nMAssay Description:Binding affinity to GOT1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails PubMed