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Found 42 Enz. Inhib. hit(s) with all data for entry = 50017303
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600976(CHEMBL5200260)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50601000(CHEMBL5206774)
Affinity DataEC50:  900nMAssay Description:Partial agonist activity at FXR (unknown origin) expressed in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600978(CHEMBL5184616)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600979(CHEMBL5188201)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50167161((E)-3-{3-[Cyclohexanecarbonyl-(4'-dimethylamino-bi...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails PubMedMMDB

TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600980(CHEMBL5173282)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600981(CHEMBL5192609)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600982(CHEMBL5174456)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600983(CHEMBL5192926)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600984(CHEMBL5206312)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600985(CHEMBL5187641)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600986(CHEMBL5175359)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600987(CHEMBL5184376)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600988(CHEMBL5170268)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600989(CHEMBL5203101)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600990(CHEMBL5199040)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600991(CHEMBL5189501)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600992(CHEMBL5184244)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600993(CHEMBL5169348)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600994(CHEMBL5174900)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600995(CHEMBL5208979)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600996(CHEMBL5208868)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600997(CHEMBL5176088)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600998(CHEMBL1565119)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human AR expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human ERalpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GR expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600999(CHEMBL5192460)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human LXR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600999(CHEMBL5192460)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human LXR-beta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetMineralocorticoid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM19214((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human MR expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50099491(2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human PPAR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human PPAR-gamma expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human PPAR-delta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50410522(LEVONORGESTREL)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human PR-alpha expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50410522(LEVONORGESTREL)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human PR-beta expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human RAR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human RAR-beta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human RXR-alpha expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human RXR-beta expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human THR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human THR-beta expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50600977(CHEMBL5178074)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR transfected in CHO-K1 cells coexpressed with beta-galactosidase incubated for 3 to 16 hrs by PathHunter chemiluminescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed