Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50031684
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317180(2-[6-(beta-Carboline-2-ium-2-yl)hexyl]-beta-carbol...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317182(2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-car...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317181(2-[8-(beta-Carboline-2-ium-2-yl)octyl]-beta-carbol...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317178(2-Methyl-9-[12-(2-methyl-beta-carboline-9-yl)dodec...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317183(2-[11-(beta-Carboline-2-ium-2-yl)undecyl]-beta-car...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50062599(3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317185(2-[7-(beta-Carboline-2-ium-2-yl)heptyl]-beta-carbo...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50044140(2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone | ...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317184(2-[10-(beta-Carboline-2-ium-2-yl)decyl]-beta-carbo...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317188(2-[9-(beta-Carboline-2-ium-2-yl)nonyl]-beta-carbol...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317186(2-[5-(beta-Carboline-2-ium-2-yl)pentyl]-beta-carbo...)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317190(6-Hydroxy-2-[5-(6-hydroxy-beta-carboline-2-ium-2-y...)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317189(2-[3-(beta-Carboline-2-ium-2-yl)propyl]-beta-carbo...)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317187(6-Methoxy-2-[5-(6-methoxy-beta-carboline-2-ium-2-y...)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317191(2-[2-(2-{2-[2-(beta-Carboline-2-ium-2-yl)ethoxy]et...)
Affinity DataIC50:  6.09E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed