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Found 9 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50039343
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335131(4-Chloro-3-(4-methoxybenzyl)-1-(beta-D-xylopyranos...)
Affinity DataEC50:  230nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335139(4-Chloro-3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl...)
Affinity DataEC50:  306nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335143(4-Chloro-3-[4-(methylsulfanyl)benzyl]-1-(beta-D-xy...)
Affinity DataEC50:  462nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335144(4-Chloro-3-[4-(N,N-dimethylamino)benzyl]-1-(beta-D...)
Affinity DataEC50:  629nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataEC50:  429nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335146(4-Chloro-3-(4-hydroxybenzyl)-1-(beta-D-xylopyranos...)
Affinity DataEC50:  234nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335150(4-Bromo-3-(4-cyclopropylbenzyl)-1-(beta-D-xylopyra...)
Affinity DataEC50:  327nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)
Affinity DataEC50:  197nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50335145(4-Chloro-3-(4-cyclopropylbenzyl)-1-(beta-D-xylopyr...)
Affinity DataEC50:  209nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed