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Found 38 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 7430
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60887(US9200020, Table 3, Compound 2B)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60890(US9200020, Table 3 compound 5B)
Affinity DataKi:  200nM ΔG°:  -39.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60880(US9200020, Table 1, Compound 1B)
Affinity DataKi:  300nM ΔG°:  -38.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60893(US9200020, Table 3 compound 8B)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60897(US9200020, Table 3 compound 11B)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60892(US9200020, Table 3 compound 7B)
Affinity DataKi:  600nM ΔG°:  -36.9kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60890(US9200020, Table 3 compound 5B)
Affinity DataKi:  700nM ΔG°:  -36.5kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60894(US9200020, Table 3 compound 9B)
Affinity DataKi:  1.60E+3nM ΔG°:  -34.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60886(US9200020, Table 3, Compound 1B)
Affinity DataKi:  1.90E+3nM ΔG°:  -34.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60890(US9200020, Table 3 compound 5B)
Affinity DataKi:  2.40E+3nM ΔG°:  -33.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60886(US9200020, Table 3, Compound 1B)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60896(US9200020, Table 3 compound 10B)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60897(US9200020, Table 3 compound 11B)
Affinity DataKi:  3.00E+3nM ΔG°:  -32.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60880(US9200020, Table 1, Compound 1B)
Affinity DataKi:  3.60E+3nM ΔG°:  -32.3kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60894(US9200020, Table 3 compound 9B)
Affinity DataKi:  5.40E+3nM ΔG°:  -31.3kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60896(US9200020, Table 3 compound 10B)
Affinity DataKi:  5.50E+3nM ΔG°:  -31.2kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60891(US9200020, Table 3 compound 6B)
Affinity DataKi:  6.00E+3nM ΔG°:  -31.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60886(US9200020, Table 3, Compound 1B)
Affinity DataKi:  1.10E+4nM ΔG°:  -29.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60897(US9200020, Table 3 compound 11B)
Affinity DataKi:  1.30E+4nM ΔG°:  -29.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60896(US9200020, Table 3 compound 10B)
Affinity DataKi:  2.10E+4nM ΔG°:  -27.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60887(US9200020, Table 3, Compound 2B)
Affinity DataKi:  2.10E+4nM ΔG°:  -27.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60888(US9200020, Table 3, Compound 3B)
Affinity DataKi:  2.20E+4nM ΔG°:  -27.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60891(US9200020, Table 3 compound 6B)
Affinity DataKi:  2.90E+4nM ΔG°:  -26.9kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60892(US9200020, Table 3 compound 7B)
Affinity DataKi:  3.20E+4nM ΔG°:  -26.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM194495(US9200020, Table 3 compound 4)
Affinity DataKi:  3.50E+4nM ΔG°:  -26.5kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60884(US9200020, Table 1, Compound 2B)
Affinity DataKi:  4.00E+4nM ΔG°:  -26.1kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60893(US9200020, Table 3 compound 8B)
Affinity DataKi:  4.10E+4nM ΔG°:  -26.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM194495(US9200020, Table 3 compound 4)
Affinity DataKi:  4.70E+4nM ΔG°:  -25.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60892(US9200020, Table 3 compound 7B)
Affinity DataKi:  1.78E+5nM ΔG°:  -22.3kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60887(US9200020, Table 3, Compound 2B)
Affinity DataKi: >2.00E+5nM ΔG°: >-22.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60884(US9200020, Table 1, Compound 2B)
Affinity DataKi: >2.00E+5nM ΔG°: >-22.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60894(US9200020, Table 3 compound 9B)
Affinity DataKi: >2.10E+5nM ΔG°: >-21.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60888(US9200020, Table 3, Compound 3B)
Affinity DataKi: >2.20E+5nM ΔG°: >-21.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60891(US9200020, Table 3 compound 6B)
Affinity DataKi: >2.30E+5nM ΔG°: >-21.6kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60893(US9200020, Table 3 compound 8B)
Affinity DataKi: >2.40E+5nM ΔG°: >-21.5kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM194495(US9200020, Table 3 compound 4)
Affinity DataKi: >2.50E+5nM ΔG°: >-21.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60884(US9200020, Table 1, Compound 2B)
Affinity DataKi: >2.50E+5nM ΔG°: >-21.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60888(US9200020, Table 3, Compound 3B)
Affinity DataKi: >2.50E+5nM ΔG°: >-21.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent