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Found 1412 of ph data with Target = 'Beta-secretase 2'
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM276786(3-chloro-N-{4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-...)
Affinity DataKi:  0.220nMpH: 5.0Assay Description:Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
Affinity DataKi:  0.220nM ΔG°:  -56.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
Affinity DataKi:  0.220nM ΔG°:  -56.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM276793(3-fluoro-N-{4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-...)
Affinity DataKi:  0.240nMpH: 5.0Assay Description:Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242266(US9416129, 44)
Affinity DataKi:  0.240nM ΔG°:  -55.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242250(US9416129, 28)
Affinity DataKi:  0.280nM ΔG°:  -55.4kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190709(US9181236, 13)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190708(US9181236, 12)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242231(US9416129, 9)
Affinity DataKi:  0.310nM ΔG°:  -55.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM249123(US9453034, 42)
Affinity DataKi:  0.320nM ΔG°:  -55.1kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242269(US9416129, 47)
Affinity DataKi:  0.340nM ΔG°:  -54.9kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242226(US9416129, 4)
Affinity DataKi:  0.350nM ΔG°:  -54.9kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242263(US9416129, 41)
Affinity DataKi:  0.350nM ΔG°:  -54.9kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143227(US8940748, 52 | US9029362, 52 | US9687494, 52)
Affinity DataKi:  0.370nM ΔG°:  -54.7kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47353(BDBM143220 | US9029362, 173 | US9687494, 25)
Affinity DataKi:  0.370nM ΔG°:  -54.7kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143227(US8940748, 52 | US9029362, 52 | US9687494, 52)
Affinity DataKi:  0.370nM ΔG°:  -54.7kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47353(BDBM143220 | US9029362, 173 | US9687494, 25)
Affinity DataKi:  0.370nM ΔG°:  -54.7kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM276787(3-bromo-N-{4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-1...)
Affinity DataKi:  0.380nMpH: 5.0Assay Description:Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM249091(US9453034, 5)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190697(US9181236, 1)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242268(US9416129, 46)
Affinity DataKi:  0.410nM ΔG°:  -54.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143223(US8940748, 35 | US9029362, 35 | US9687494, 35)
Affinity DataKi:  0.450nM ΔG°:  -54.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143223(US8940748, 35 | US9029362, 35 | US9687494, 35)
Affinity DataKi:  0.450nM ΔG°:  -54.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM276791(8-({4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-1,1-diox...)
Affinity DataKi:  0.460nMpH: 5.0Assay Description:Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47353(BDBM143220 | US9029362, 173 | US9687494, 25)
Affinity DataKi:  0.470nM ΔG°:  -54.1kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143224(US8940748, 173 | US9687494, 173)
Affinity DataKi:  0.470nM ΔG°:  -54.1kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47353(BDBM143220 | US9029362, 173 | US9687494, 25)
Affinity DataKi:  0.470nM ΔG°:  -54.1kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 were determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190700(US9181236, 4)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM249100(US9453034, 12b)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190711(US9181236, 15)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM249121(US9453034, 40)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242270(US9416129, 48)
Affinity DataKi:  0.630nM ΔG°:  -53.4kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242938(US9422277, 1)
Affinity DataKi:  0.690nM ΔG°:  -53.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM242229(US9416129, 7)
Affinity DataKi:  0.730nM ΔG°:  -53.0kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM228057(US10047098, 85)
Affinity DataKi:  0.760nMpH: 5.0Assay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM249099(US9453034, 12a)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190714(US9181236, 18)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM276788(7-bromo-N-{4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-1...)
Affinity DataKi:  0.810nMpH: 5.0Assay Description:Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM249095(US9453034, 9)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190773(US9181236, 62g)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190699(US9181236, 3)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM236599(US9365589, 1z)
Affinity DataKi:  1nMpH: 5.0Assay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM236594(US9365589, 1u)
Affinity DataKi:  1nMpH: 5.0Assay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM256742(US9489013, 13)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50's at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM256761(US9489013, 32)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50's at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM256765(US9489013, 36)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50's at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM244045(US9428476, 1a)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:BACE-mediated hydrolysis of this peptide results in an increase in relative fluorescence (RFU) at 620 nm after excitation with 320 nm light Inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM244046(US9428476, 1b)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:BACE-mediated hydrolysis of this peptide results in an increase in relative fluorescence (RFU) at 620 nm after excitation with 320 nm light Inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM258951(US9499502, 9ba)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM190761(US9181236, 58)
Affinity DataKi:  1nM ΔG°:  -52.2kJ/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISE...More data for this Ligand-Target Pair
In DepthDetails US Patent
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