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Found 21 of ph data with Target = 'Carbonic anhydrase 5B, mitochondrial'
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM25896(EMD 486019 | [2-(cycloheptylmethyl)-1,1-dioxo--ben...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM10883(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)
Affinity DataKi:  21nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM50210256(CHEMBL26300 | Sulfamic acid (3aS,5aR,8aR,8bS)-2,2,...)
Affinity DataKi:  30nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  34nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  45nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  54nM ΔG°:  -41.5kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  54nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  54nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26999(4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...)
Affinity DataKi:  91nM ΔG°:  -39.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26998(6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-...)
Affinity DataKi:  134nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM50352643(CHEMBL1822699)
Affinity DataKi:  310nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM50352644(CHEMBL1822700)
Affinity DataKi:  321nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM239155(7-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  380nM ΔG°:  -34.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM50352646(CHEMBL1822702)
Affinity DataKi:  427nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  430nM ΔG°:  -33.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM50352645(CHEMBL1822701)
Affinity DataKi:  513nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataKi:  720nM ΔG°:  -35.1kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM248142(Grayanotoxin III (GTX3))
Affinity DataKi:  740nM ΔG°:  -35.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM50095994(3-Cyano-7-hydroxycoumarin (2) | 7-Hydroxy-2-oxo-2H...)
Affinity DataKi:  1.87E+3nM ΔG°:  -30.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Affinity DataKi:  6.03E+3nM ΔG°:  -29.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank