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Found 196
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50369190(CHEMBL4163133)
Affinity DataKi:  15nMAssay Description:Binding affinity to APC (unknown origin) assessed as inhibition constant by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50407493(CHEMBL5288446)
Affinity DataKi:  15nMAssay Description:Relative potency against Histamine H1 receptor in rat aortaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50407492(CHEMBL5280732)
Affinity DataKi:  120nMAssay Description:Apparent pA2 value of compound at 50 nM concentration of mepyramine in rat aortaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50407464(CHEMBL5289275)
Affinity DataKi:  2.41E+3nMAssay Description:Apparent pA2 value of compound at 10 nM concentration of mepyramine in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50407467(CHEMBL5289169)
Affinity DataKi:  3.12E+3nMAssay Description:Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50407491(CHEMBL5282293)
Affinity DataKi:  3.80E+3nMAssay Description:Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50407461(CHEMBL5274458)
Affinity DataKi:  4.46E+4nMAssay Description:Tetsed for Antagonistic activity at histamine H3 receptor in guinea pig ileal longitudinal muscle in the presence of mepyramine at a concentration of...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM50481595(CHEMBL5287183)
Affinity DataKi:  4.46E+4nMAssay Description:Binding affinity to APC (unknown origin) assessed as inhibition constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM273137(US10071086, Compound 443)
Affinity DataIC50:  1nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM269261(US10071086, Compound 9)
Affinity DataIC50:  1.20nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM271118(US10071086, Compound 382)
Affinity DataIC50:  3nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM269257(US10071086, Compound 5)
Affinity DataIC50:  3.90nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM271120(US10071086, Compound 440)
Affinity DataIC50:  4nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM269259(US10071086, Compound 7)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM269254(US10071086, Compound 1)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM269255(US10071086, Compound 2)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270609(US10071086, Compound 158)
Affinity DataIC50:  8nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275757(US10071086, Compound 785)
Affinity DataIC50:  10nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270606(US10071086, Compound 114)
Affinity DataIC50:  11nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275764(US10071086, Compound 888)
Affinity DataIC50:  12nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270617(US10071086, Compound 229)
Affinity DataIC50:  12nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270451(US10071086, Compound 18)
Affinity DataIC50:  13nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275758(US10071086, Compound 793)
Affinity DataIC50:  16nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275761(US10071086, Compound 803)
Affinity DataIC50:  17nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275735(US10071086, Compound 605)
Affinity DataIC50:  18nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275734(US10071086, Compound 602)
Affinity DataIC50:  18nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275730(US10071086, Compound 590)
Affinity DataIC50:  20nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270480(US10071086, Compound 24)
Affinity DataIC50:  21nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270306(US10071086, Compound 12)
Affinity DataIC50:  21nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275609(US10071086, Compound 552)
Affinity DataIC50:  22nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275503(US10071086, Compound 458)
Affinity DataIC50:  22nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275754(US10071086, Compound 765)
Affinity DataIC50:  27nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275740(US10071086, Compound 643)
Affinity DataIC50:  30nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270471(US10071086, Compound 22)
Affinity DataIC50:  32nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275759(US10071086, Compound 797)
Affinity DataIC50:  32nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275598(US10071086, Compound 551)
Affinity DataIC50:  33nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275738(US10071086, Compound 635)
Affinity DataIC50:  34nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275737(US10071086, Compound 621)
Affinity DataIC50:  36nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM269255(US10071086, Compound 2)
Affinity DataIC50:  38nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275749(US10071086, Compound 728)
Affinity DataIC50:  39nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275666(US10071086, Compound 581)
Affinity DataIC50:  48nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275495(US10071086, Compound 452)
Affinity DataIC50:  48nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275752(US10071086, Compound 758)
Affinity DataIC50:  48nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275762(US10071086, Compound 818)
Affinity DataIC50:  50nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM271093(US10071086, Compound 376)
Affinity DataIC50:  51nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275659(US10071086, Compound 557)
Affinity DataIC50:  53nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270853(US10071086, Compound 346)
Affinity DataIC50:  56nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270854(US10071086, Compound 352)
Affinity DataIC50:  57nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM270830(US10071086, Compound 325)
Affinity DataIC50:  58nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))TBA
LigandPNGBDBM275763(US10071086, Compound 827)
Affinity DataIC50:  63nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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