Compile Data Set for Download or QSAR
maximum 50k data
Found 157 of ec50 data for polymerid = 50000279,50004158
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597260(CHEMBL5182897 | US20230391758, Compound 20)
Affinity DataEC50:  0.0200nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597260(CHEMBL5182897 | US20230391758, Compound 20)
Affinity DataEC50:  0.0200nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597261(CHEMBL5170109 | US20230391758, Compound 21)
Affinity DataEC50:  0.0210nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597261(CHEMBL5170109 | US20230391758, Compound 21)
Affinity DataEC50:  0.0210nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597262(CHEMBL5191157 | US20230391758, Compound 22)
Affinity DataEC50:  0.0230nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597262(CHEMBL5191157 | US20230391758, Compound 22)
Affinity DataEC50:  0.0230nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645674(N-(pyridin-3-yl)-8-(2-(2,2,2- trifluoroethoxy)phen...)
Affinity DataEC50:  0.0290nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597264(CHEMBL5195638 | US20230391758, Compound 24)
Affinity DataEC50:  0.0440nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597264(CHEMBL5195638 | US20230391758, Compound 24)
Affinity DataEC50:  0.0440nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597263(CHEMBL5177098 | US20230391758, Compound 23)
Affinity DataEC50:  0.0440nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597263(CHEMBL5177098 | US20230391758, Compound 23)
Affinity DataEC50:  0.0440nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50597265(CHEMBL5197108)
Affinity DataEC50:  0.0470nMAssay Description:Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639323(7-(2-chloro-5-cyano-phenyl)- N-[(1R,3S)-3- hydroxy...)
Affinity DataEC50:  0.0470nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645729(6-[6-chloro-8-[2-(2,2,2- trifluoroethoxy)phenyl]im...)
Affinity DataEC50:  0.0610nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639300(N-(1,6-naphthyridin-2-yl)-7- (1,3,5-trimethylpyraz...)
Affinity DataEC50:  0.0650nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645720(6-fluoro-N-(pyridin-3-yl)-8-(2-(2,2,2- trifluoroet...)
Affinity DataEC50:  0.0830nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639301(7-(5-cyano-2-methoxy-phenyl)- N-(4-hydroxynorborna...)
Affinity DataEC50:  0.0970nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639302(7-[5-cyano-2- (difluoromethoxy)phenyl]-N- (4-hydro...)
Affinity DataEC50:  0.100nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639324(Cis-7-(5-cyano-2-isopropoxy- phenyl)-5-fluoro-N-(3...)
Affinity DataEC50:  0.100nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645715(N-(4-methylpyridin-3-yl)-8-(2-(2,2,2- trifluoroeth...)
Affinity DataEC50:  0.150nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639303(5-chloro-7-(5-cyano-2- methoxy-phenyl)-N-[(1R,3S)-...)
Affinity DataEC50:  0.170nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645690(N-(cis-3- (hydroxymethyl)cyclohexyl)-8-(2- (2,2,2-...)
Affinity DataEC50:  0.230nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639325(Cis or trans-5-fluoro-N-(4- hydroxy-1-methyl- cycl...)
Affinity DataEC50:  0.240nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639317(US20230391758, Compound 19)
Affinity DataEC50:  0.260nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645683(6-chloro-N-(trans-4- hydroxycyclohexyl)-8-(2-(2,2,...)
Affinity DataEC50:  0.360nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM576437(WO2022115301, Example 23)
Affinity DataEC50:  0.410nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645716(N-(4-fluoropyridin-3-yl)-8-(2-(2,2,2- trifluoroeth...)
Affinity DataEC50:  0.450nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639312((R and S)-N-(4,4-difluoro-3- piperidyl)-7-[2-(2,2,...)
Affinity DataEC50:  0.480nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645710((2,5-dioxa-8-azaspiro[3.5]nonan-8- yl)(8-(2-(2,2,2...)
Affinity DataEC50:  0.510nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639326(Cis-7-(5-chloro-2-methoxy- phenyl)-5-fluoro-N-[3- ...)
Affinity DataEC50:  0.600nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645681(6-chloro-N-((1S,2R,4S and 1R, 2S,4R)-2-fluoro-4- h...)
Affinity DataEC50:  0.720nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639336(US20230391758, Compound 38)
Affinity DataEC50:  0.790nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645685(US20240018140, Compound 26 | cis or trans-6-fluoro...)
Affinity DataEC50:  0.790nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639327(7-(5-cyano-2-isopropoxy- phenyl)-5-fluoro-N-(2- hy...)
Affinity DataEC50:  0.820nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645675(N-(trans-4-fluoropiperidin-3-yl)-8-(2- (2,2,2- tri...)
Affinity DataEC50:  0.830nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645679(6-chloro-N-(1-hydroxy-2- methylpropan-2-yl)-8-(2-(...)
Affinity DataEC50:  0.860nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639304(7-[5-chloro-2- (difluoromethoxy)-3-pyridyl]- N-(4-...)
Affinity DataEC50:  0.870nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639315(5-fluoro-N-[4- (hydroxymethyl)-1- bicyclo[2.2.2]oc...)
Affinity DataEC50:  0.890nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645663((S)-6-chloro-N-(tetrahydrofuran-3- yl)-8-(2-(2,2,2...)
Affinity DataEC50:  0.910nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM576435(WO2022115301, Example 21)
Affinity DataEC50:  0.910nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM576438(WO2022115301, Example 24)
Affinity DataEC50:  0.930nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645673((R and S)-6-chloro-N-(3- methyltetrahydrofuran-3-y...)
Affinity DataEC50:  0.970nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639299(5-fluoro-N-(trans-4-(hydroxymethyl)cyclohexyl)-7-(...)
Affinity DataEC50:  0.990nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639305(N-(3-pyridyl)-7-[2-(2,2,2- trifluoroethoxy)phenyl]...)
Affinity DataEC50:  0.990nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639306(7-(5-chloro-2-methoxy-3- pyridyl)-N-(4- hydroxynor...)
Affinity DataEC50:  1.10nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645665((6-chloro-8-(2-(2,2,2- trifluoroethoxy)phenyl)imid...)
Affinity DataEC50:  1.20nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645676((R and S)-N-(4,4-difluoropiperidin-3- yl)-8-(2-(2,...)
Affinity DataEC50:  1.20nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645686(6-fluoro-N-(cis-4- (hydroxymethyl)cyclohexyl)-8-(2...)
Affinity DataEC50:  1.30nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645724(US20240018140, Compound 65 | [6-chloro-8-[2-(2,2,2...)
Affinity DataEC50:  1.30nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639334((R or S)-N-(4,4-difluoro-3- piperidyl)-7-(2- propo...)
Affinity DataEC50:  1.40nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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