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Found 3 of kd data for polymerid = 7082,50002235
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505257(CHEMBL4471012)
Affinity DataKd:  460nMAssay Description:Binding affinity to human recombinant Nav1.5 by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50521571(CHEMBL4464990)
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of full length human Nav1.5 expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM76858(US9546164, 580 | US9694002, 580)
Affinity DataKd:  370nMAssay Description:Binding affinity to human recombinant Nav1.5 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed