TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Uncompetitive inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldeh...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Uncompetitive inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Uncompetitive inhibition of Wistar rat lens aldose reductase using D,L-glyceraldehyde as substrate by double reciprocal plot analysisMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: >300nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity of the compound was determined towards rabbit aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: >500nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 950nM ΔG°: -34.4kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nM ΔG°: -33.2kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.00E+3nM ΔG°: -32.5kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.11E+3nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli using DL-glyceraldehyde as substrate by double reciproca...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of beef brain NADP-dependent aldehyde reductase using p-nitrobenzaldehyde by competitive inhibition assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.50E+3nM ΔG°: -32.0kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.50E+3nM ΔG°: -31.1kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.40E+3nM ΔG°: -30.6kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
Affinity DataKi: 5.10E+3nMAssay Description:Inhibition of beef brain NADP-dependent aldehyde reductase using p-nitrobenzaldehyde by competitive inhibition assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.20E+3nM ΔG°: -29.7kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of beef brain NADP-dependent aldehyde reductase using p-nitrobenzaldehyde by competitive inhibition assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 7.30E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 8.10E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 9.30E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.05E+4nMAssay Description:Inhibition of Wistar rat lens aldose reductase 2 using NADPH as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of Wistar rat lens aldose reductase 2 using NADPH as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of beef brain NADP-dependent aldehyde reductase using p-nitrobenzaldehyde by competitive inhibition assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.30E+4nM ΔG°: -27.9kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.77E+4nMAssay Description:Inhibition of Wistar rat lens aldose reductase 2 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences
Curated by ChEMBL
Slovak Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.79E+4nMAssay Description:Inhibition of Wistar rat lens aldose reductase 2 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.55E+4nM ΔG°: -26.2kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.42E+4nM ΔG°: -25.5kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair